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Kidney transplantation performed before dialysis is ever needed — associated with the best graft and patient outcomes.
Preemptive transplant means receiving a kidney transplant while still in CKD stage 5 without having started dialysis. Outcomes are the best of any transplant pathway: patients avoid dialysis-associated morbidity (vascular access, infections, cardiovascular stress), and registry data show better graft and patient survival than transplant-after-dialysis. It requires early referral and evaluation, plus a living donor or listing timing that aligns with the eGFR trajectory. It is the standard goal in pediatric CKD and increasingly recommended in adults.
A surgical procedure in which a healthy kidney from a living or deceased donor is transplanted into a patient with end-stage renal disease to restore kidney function.
A person who donates a kidney during their lifetime — usually a family member or friend — with outcomes generally better than deceased-donor transplants.
A progressive condition characterized by gradual loss of kidney function over months or years, classified into 5 stages based on eGFR.
A calculated value estimating the rate at which kidneys filter blood, used to diagnose and stage chronic kidney disease.
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