A calculated value estimating the rate at which kidneys filter blood, used to diagnose and stage chronic kidney disease.
eGFR is calculated from serum creatinine levels using standardized equations. The two main formulas are: (1) CKD-EPI (Chronic Kidney Epidemiology Collaboration) — the current recommended formula, more accurate at higher GFR levels; (2) MDRD (Modification of Diet in Renal Disease) — older formula, still used in some labs. The calculation accounts for age, sex, and sometimes race. Normal eGFR is ≥90 mL/min/1.73m². A declining eGFR trend over time indicates progressive kidney damage and triggers clinical interventions to slow progression.
A progressive condition characterized by gradual loss of kidney function over months or years, classified into 5 stages based on eGFR.
A waste product of muscle metabolism filtered by the kidneys; serum creatinine levels are used to estimate GFR and monitor kidney function over time.
The medical specialty focused on the diagnosis, treatment, and management of kidney diseases, including dialysis and transplant care.
A calculated value estimating the rate at which kidneys filter blood, used to diagnose and stage chronic kidney disease.
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This content is a general reference, not medical advice, a diagnosis, or a treatment plan. Do not change your diet, fluids, medicines, or dialysis plan without your nephrologist or renal dietitian. Individual recommendations depend on your labs, medications, conditions, and care plan.