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Acute kidney injury occurring within 48 hours of receiving iodinated contrast media, most relevant in people with pre-existing CKD and diabetes.
Contrast-induced acute kidney injury is a rise in creatinine (typically ≥0.3 mg/dL or 1.5× baseline) within 48 hours of iodinated contrast exposure. Risk concentrates in patients with eGFR below 30, diabetes, dehydration, and concurrent nephrotoxin use. The only proven prevention is hydration; NAC is no longer recommended. IV contrast risk is lower than historically believed, but metformin is held per label (day of scan + 48 hours) and NSAIDs are paused. In dialysis patients, contrast is safe without special scheduling.
A waste product of muscle metabolism filtered by the kidneys; serum creatinine levels are used to estimate GFR and monitor kidney function over time.
A calculated value estimating the rate at which kidneys filter blood, used to diagnose and stage chronic kidney disease.
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