Zyloprim / Zyloric • Xanthine oxidase inhibitor • Kidney function: ≥45 mL/min/1.73m² (or CrCl >50)
The recommended dose of Allopurinol and Kidneys at ≥45 mL/min/1.73m² (or CrCl >50) — with monitoring notes for kidney disease and dialysis.
Start 100 mg/day; titrate every 2-5 weeks to serum urate <6.0 mg/dL.
Standard titration. Continue during flares — stopping worsens them.
Doses in this guide follow drug labels and renal-dosing references at each eGFR/CrCl level. Always confirm with your prescriber and pharmacy — your specific dose depends on other medications, conditions, and lab results.
Full Allopurinol and Kidneys kidney guideAllopurinol and Kidneys has its own monitoring requirements (eGFR, potassium, drug levels, or blood counts). These become more frequent as kidney function falls. Report unusual weakness, irregular heartbeat, or new side effects promptly.
Interactive drug-dosing tool